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Cancer: Lymphoma
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Total 25227 results found since Jan 2013.
Duodenal-type follicular lymphoma in < sup > 18 < /sup > F-FDG PET/CT imaging: a case report
We report a case of a 36-year-old male patient with multiple, small, gray polypoid lesions in the descending duodenum which were detected by esophagogastroduodenoscopy. The pathological diagnosis was low-grade D-FL. 18F-FDG PET/CT was performed for staging and revealed the pancreas and peripheral lymph nodes were involved by FL, with a clinical IV stage. The patient underwent a bone marrow smear cytology, which revealed no bone marrow abnormalities, and excluded bone marrow involvement. He was treated with six cycles of chemotherapy using the R-CHOP regimen and reached complete remission.PMID:37736494 | PMC:PMC10509290
Source: Molecular Medicine - September 22, 2023 Category: Molecular Biology Authors: Wenpeng Huang Fangfang Chao Yushuo Peng Xiaoyue Zhang Qi Yang Lele Song Liming Li Lei Kang Source Type: research
Paraneoplastic arthritis: a series of 92 cases
CONCLUSION: As a result, although PA is a rare condition, it can be confused with many rheumatological diseases. The most commonly involved joint is the knee joint, followed by the ankle and hand-wrist. Autoantibody negativity, high LDH level, and arthritis unresponsive to treatment constitute important clues for diagnosis.PMID:37738571 | DOI:10.1093/rheumatology/kead500
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: B ünyamin Kısacık Fatih Albayrak Mehmet Ali Balc ı Emrah Koc Source Type: research
Oncolytic virus oHSV2 combined with PD-1/PD-L1 inhibitors exert antitumor activity by mediating CD4 + T and CD8 + T cell infiltration in the lymphoma tumor microenvironment
Autoimmunity. 2023 Dec;56(1):2259126. doi: 10.1080/08916934.2023.2259126. Epub 2023 Sep 22.ABSTRACTA novel therapeutic regimen showed that the oncolytic type II herpes simplex virus (oHSV2) was able to prevent colorectal cancer growth, recurrence, and metastasis. However, no study has yet explored whether oHSV2 has an impact on the development of diffuse large B-cell lymphoma (DLBCL). We chose the clinical chemotherapeutic drug doxorubicin (DOX) as a positive control to evaluate the effect of oHSV2 infection on the apoptotic, invasive, and proliferative capacity of DLBCL cells. We next further explored the therapeutic effi...
Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Jingbo Zhang Yiwei Guo Huiying Fang Xiuchen Guo Lina Zhao Source Type: research
Circ_0000396 suppresses the proliferation and inflammation of rheumatoid arthritis synovial fibroblasts by targeting miR-574-5p/RSPO1 axis
CONCLUSION: Circ_0000396 restrained the proliferation and inflammation and induced the apoptosis of RASFs by mediating miR-574-5p/RSPO1 axis, which provided novel potential targets for RA treatment.PMID:37737195 | DOI:10.1186/s13018-023-04117-5
Source: Cell Research - September 22, 2023 Category: Cytology Authors: Hongchao Yu Jin Yang Kun Chen Wulin Kang Fengfeng Zhu Source Type: research
Piperlongumine induces apoptosis and autophagy via the PI3K/Akt/mTOR pathway in KB human cervical cancer cells
Food Chem Toxicol. 2023 Sep 19:114051. doi: 10.1016/j.fct.2023.114051. Online ahead of print.ABSTRACTNatural products are continuously being researched to develop safe and effective treatment options for cervical cancer, the fourth most common cancer in women. Piperlongumine (PL), an amide alkaloid mainly present in long pepper, exhibits neuroprotective and anti-cancer properties. However, the specific effect of PL in cervical cancer and the relationship between the anti-cancer pathway and autophagy remain unclear. Therefore, we aimed to investigate PL-induced apoptosis in KB human cervical cancer cells and the relationshi...
Source: Food and Chemical Toxicology - September 21, 2023 Category: Food Science Authors: Eun-Ji Han Eun-Young Choi Su-Ji Jeon Sang-Woo Lee Jun-Mo Moon Soo-Hyun Jung Bumseok Kim Sung-Dae Cho Jeong-Seok Nam Changsun Choi Jeong-Hwan Che Ji-Youn Jung Source Type: research
Patterns of PET-positive residual tissue at interim restaging and risk of treatment failure in advanced-stage Hodgkin's lymphoma: an analysis of the randomized phase III HD18 trial by the German Hodgkin Study Group
CONCLUSION: PET-2-positive residuals of AS-HL are mostly located in the mediastinum, and a majority of patients have few affected regions. The risk of progression was twofold higher in patients with more than two positive regions in PET-2.PMID:37735258 | DOI:10.1007/s00259-023-06431-w
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Justin Ferdinandus Lutz van Heek Katrin Roth Markus Dietlein Hans-Theodor Eich Christian Baues Peter Borchmann Carsten Kobe Source Type: research
Britanin inhibits titanium wear particle ‑induced osteolysis and osteoclastogenesis
Mol Med Rep. 2023 Nov;28(5):205. doi: 10.3892/mmr.2023.13092. Epub 2023 Sep 21.ABSTRACTWear particle‑induced osteolysis is a serious complication that occurs in individuals with titanium (Ti)‑based implants following long‑term usage due to loosening of the implants. The control of excessive osteoclast differentiation and inflammation is essential for protecting against wear particle‑induced osteolysis. The present study evaluated the effect of britanin, a pseudoguaianolide sesquiterpene isolated from Inula japonica, on osteoclastogenesis in vitro and Ti particle‑induced osteolysis in vivo. The effect of britanin ...
Source: Molecular Medicine - September 21, 2023 Category: Molecular Biology Authors: Ju Ang Kim Soomin Lim Hye Jung Ihn Jung-Eun Kim Kyungmoo Yea Jimin Moon Hyukjae Choi Eui Kyun Park Source Type: research
Outcomes of Patients Treated With RCHOP With a PET-Adapted Approach for Consolidative Radiotherapy: A Retrospective Single-Center Study at the Royal Marsden Hospital
CONCLUSION: CRT may be omitted in patients with a negative end of treatment PET scans; however, careful observation may also obviate the need for CRT in PET positive patients.PMID:37734988 | DOI:10.1016/j.clml.2023.08.021
Source: Clinical Lymphoma and Myeloma - September 21, 2023 Category: Cancer & Oncology Authors: Su Li Bhupinder Sharma Siraj Yusuf Vasiliki Michalarea Mary Gleeson Laura Hickmott Andrew Wotherspoon Ayoma D Attygalle Katherine Vroobel Simon O'Connor Yong Du Andrea Kuhnl Sunil Iyengar Dima El-Sharkawi Ian Chau David Cunningham Source Type: research
Collision tumor of primary malignant lymphoma and adenocarcinoma in the colon diagnosed by molecular pathology: A case report and literature review
CONCLUSION: Based on pathological and genetic analysis, surgery combined with chemotherapy or chemoradiotherapy may have good therapeutic effects for collision tumor.PMID:37731579 | PMC:PMC10507543 | DOI:10.12998/wjcc.v11.i26.6289
Source: Clinical Colorectal Cancer - September 21, 2023 Category: Cancer & Oncology Authors: Meng Jiang Xiao-Ping Yuan Source Type: research
Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies in the targeted therapy era
World J Gastroenterol. 2023 Sep 7;29(33):4942-4961. doi: 10.3748/wjg.v29.i33.4942.ABSTRACTHepatitis due to hepatitis B virus (HBV) reactivation can be serious and potentially fatal, but is preventable. HBV reactivation is most commonly reported in patients receiving chemotherapy, especially rituximab-containing therapy for hematological malignancies and those receiving stem cell transplantation. Patients with inactive and even resolved HBV infection still have persistence of HBV genomes in the liver. The expression of these silent genomes is controlled by the immune system. Suppression or ablation of immune cells, most imp...
Source: World Journal of Gastroenterology : WJG - September 21, 2023 Category: Gastroenterology Authors: Joyce Wing Yan Mak Alvin Wing Hin Law Kimmy Wan Tung Law Rita Ho Carmen Ka Man Cheung Man Fai Law Source Type: research
Early Mortality as a Quality Indicator in Frontline and Salvage Acute Myeloid Leukemia
CONCLUSIONS: Quality measure algorithms should incorporate a risk mortality index related to leukemia vs. other tumors and benign conditions and a risk mortality index related to the treatment status of leukemia (salvage vs. frontline therapy).PMID:37730483 | DOI:10.1016/j.clml.2023.08.016
Source: Clinical Lymphoma and Myeloma - September 20, 2023 Category: Cancer & Oncology Authors: Koji Sasaki Farhad Ravandi Courtney DiNardo Mary Alma Welch Tapan Kadia Hagop Kantarjian Source Type: research
Tumor-infiltrating normal B cells revealed by immunoglobulin repertoire clonotype analysis are highly prognostic and crucial for antitumor immune responses in DLBCL
CONCLUSIONS: TIL-B frequency is a significant prognostic factor in DLBCL and plays a crucial role in antitumor immune responses. This study provides novel insights into the prognostic determinants in DLBCL and TIL-B functions with important therapeutic implications.PMID:37728879 | DOI:10.1158/1078-0432.CCR-23-1554
Source: Clinical Cancer Research - September 20, 2023 Category: Cancer & Oncology Authors: Zijun Y Xu-Monette Yong Li Thomas Snyder Tiantian Yu Tingxun Lu Alexandar Tzankov Carlo Visco Govind Bhagat Wenbin Qian Karen Dybkaer April Chiu Wayne Tam Youli Zu Eric D Hsi Fredrick B Hagemeister Yingjun Wang Heounjeong Go Maurilio Ponzoni Andr és J M Source Type: research
